Smoothelin mw

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August undefined, 2024

WebA smoothelin-deficient mouse model may help to establish the role of smoothelin-A in intestinal contraction and provide a model for myogenic chronic intestinal pseudo-obstruction. Methods: We used gene targeting to investigate the function of smoothelin-A … WebSmoothelin is a novel smooth muscle-specific contractile protein expressed only by fully differentiated smooth muscle cells, and not by proliferative or noncontractile smooth muscle cells and myofibroblasts. ... Datta MW, Amin MB (2007). Further characterization of the …

Hans J. Vogel University of Calgary Contacts

Web4 Aug 2008 · Therefore, it is unlikely that smoothelin-B plays a role in the regulation of SMC differentiation, as was previously suggested on the basis of its strict contractile phenotype-specific expression. 23 Second, arterial contractility was similarly reduced in mice lacking both smoothelins and mice lacking only smoothelin-B, indicating that smoothelin-B is the … WebSmoothelin is a protein that in humans is encoded by the SMTN gene. [5] [6] [7] This gene encodes a structural protein that is found exclusively in contractile smooth muscle cells. It associates with stress fibers and constitutes part of the cytoskeleton. smalles drawer kitchen cabinet

Anti-Smoothelin antibody (GTX32885) GeneTex

Web1 Jan 2002 · Smoothelin, a cytoskeletal protein, exists in a large isoform specifically expressed in vascular smooth muscle cells, and a small visceral isoform generated by a downstream transcriptional start site. Using fusions to the green fluorescent protein, we could show that both smoothelin isoforms are localized at actin containing filaments and … Web31 Mar 2024 · Smoothelin has 2 isoforms, smoothelin-A (59 kDa) and smoothelin-B (102 kDa), with smoothelin-A expressed in visceral SMCs and smoothelin-B expressed in VSMCs . Desmin Indirect immunofluorescence showed that in skeletal muscle, desmin was found … WebAnti-Smoothelin antibody (GTX32885) GeneTex Back Primary Antibodies Secondary Antibodies Antibody Panels ELISA Antibody Pairs & Kits Isotype Controls Proteins & Peptides Slides Lysates Serums & Plasmas Reagents Research Kits Research Tools Back … smalles heart monitor

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Fibroblasts and myofibroblasts in wound healing CCID

Websmoothelin-B knockout mice (Smtn-B /) is described else-where (Rensen et al, unpublished data). In these mice, exons 3–6 of the smoothelin gene are removed and smoothelin-B synthesis is absent; however, smoothelin-A synthesis is not affected. All animal studies … http://www.cellmarque.com/antibodies/CM/2117/Smoothelin_R4A song hold me touch me kiss meWebsmoothelin Calculated MW: 940 aa, 102 kDa Observed MW: 117 kDa Purification Method: Antigen Affinity purified Recommended Dilutions: WB 1:500-1:1000 ... Background Information SMTN, also named as Smoothelin, is a 917 amino acid protein, which … song hold on in movie breakthrough

"WebRegulatory relationships of SMTN. Smoothelin is a cytoskeletal protein specifically expressed in differentiated smooth muscle cells and has been shown to colocalize with smooth muscle alpha actin [6]. In stented pig coronary vessels, LPP was expressed in the … " - Smoothelin mw

Smoothelin mw

Hans J. Vogel University of Calgary Contacts

WebSpecifically, myofibroblasts in most cases are negative for SM cell markers such as SM myosin heavy chain, 14 n-caldesmon, 15 and smoothelin. 16 Desmin has also been used as a negative marker of myofibroblasts. Generally, SM cells express desmin and vimentin as well as SM myosin, while myofibroblasts express only vimentin. Web11 Jan 2024 · Smoothelin is a constituent of the smooth muscle cell cytoskeleton protein exclusively found in differentiated smooth muscle cells (SMC). Cells with SMC-like characteristics, such as myofibroblasts and myoepithelial cells, as well as skeletal and cardiac muscle do not contain smoothelin. 1,2 To distinguish bladder muscularis …

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WebBuy Anti-Smoothelin, item number: ARG59311.50 from Arigo Biolaboratories at Biomol! Webwww.ncbi.nlm.nih.gov

Web13 Jan 2014 · Myofibroblasts are identified by the neo-expression of α-smooth muscle actin (α-SMA) and the absence of desmin, smooth muscle myosin heavy chain (SM-MHC), h-caldesmon, and smoothelin distinguishing them from SMCs. They combine … WebBoth recognize a single protein species of about 117 kD in coronary arteries, corresponding to the large vascular-specific smoothelin isoform and in bladder only the anti-smo2 recognizes a band at ...

Web7 Jun 2010 · Smoothelin immunohistochemistry is a useful adjunct for assessing muscularis propria invasion in bladder carcinoma. Aims: To prospectively evaluate the utility of smoothelin immunohistochemical expression for the evaluation of muscularis propria … Web21 Mar 2024 · SMTN (Smoothelin) is a Protein Coding gene. Diseases associated with SMTN include Atrophy Of Prostate and Glomangiomyoma . Gene Ontology (GO) annotations related to this gene include actin binding and structural constituent of muscle .

Web5 Oct 2024 · Hyperthyroidism triggers a glycolytic shift in skeletal muscle (SKM) by altering the expression of metabolic proteins, which is often accompanied by peripheral insulin resistance. Our previous results show that smoothelin-like protein 1 (SMTNL1), a transcriptional co-regulator, promotes insulin sensitivity in SKM. Our aim was to elucidate …

Web19 Aug 2010 · Smoothelin is a specific and robust marker for distinction of muscularis propria and muscularis mucosae in the gastrointestinal tract. Aims: As tumour specimens and biopsy specimens become smaller, recognition of anatomical structures relevant for … song hold on a little bit tighterWebImmunohistochemical analysis of paraffin-embedded human colon tissue labeling Smoothelin with ab219652 at 1/8000 dilution, followed by Goat Anti-Rabbit IgG H&L (HRP) Ready to use. Cytoplasmic staining on vascular smooth muscle and visceral smooth … song hold on change is comingWeb2 Dec 2024 · As the focus of this review, the smoothelin and smoothelin-like family members represent a family of poorly understood muscle proteins that appear to act as structural components of the contractile apparatus. The protein family is characterized by … smalles drawer cabinetWeb12 Aug 2024 · Differentiated smooth muscle cells Positive staining - disease Cytoplasmic staining: benign smooth muscle tumors, GI leiomyosarcomas (24%, Am J Surg Pathol 2009;33:1795 ) Nuclear staining: GI leiomyosarcomas (41%), GIST (22%) Negative staining … small esky lunch boxWebSmoothelin antibody LS-C409024 is an unconjugated rabbit polyclonal antibody to Smoothelin from human. It is reactive with human, mouse and rat. Validated for WB. song hold on i\u0027m comingWebSmoothelin Antibodies Antibodies that detect Smoothelin can be used in several scientific applications, including Western Blot, Immunohistochemistry and Immunocytochemistry. These antibodies target Smoothelin in Human, Mouse, Rat, Feline and Chicken samples. … song hold my hand hootie and blowfishWeb25 May 2001 · i: Smoothelin transcripts in the primary smooth muscle cells (SMC) of the descending aorta of embryo shown in b. j–n: Smoothelin expression in descending and ascending (Aao) aorta at different stages of development. Smoothelin was confined to … song hold on ian gomm